I am not by any means a recovery expert, so I will not try to give you advise on that part of your question.
How did you lose access to the drive? If not a physical problem with the drive, it could be a malware issue that is locking you out of your access to the drive.
I would suggest you sign up at one of the free Malware Removal sites below. They are also able to work through Windows issues. Do not try to do anything on your own as it could make things harder for the Malware Removal expert at that site to help you. Choose one and stay there until your system is clean.
http://www.bleepingcomputer.com/
http://www.geekstogo.com/forum/
http://www.cybertechhelp.com/forums/
http://forums.whatthetech.com/